Characterization of T cell subpopulations involved in the pathogenesis of asthma and allergic diseases.

@article{Yssel2000CharacterizationOT,
  title={Characterization of T cell subpopulations involved in the pathogenesis of asthma and allergic diseases.},
  author={Hans Yssel and Herv{\'e} Groux},
  journal={International archives of allergy and immunology},
  year={2000},
  volume={121 1},
  pages={10-8}
}
Allergic asthma is a complex and heterogeneous disease which is characterized by intermittent reversible airway obstruction, chronic inflammation of the airways, bronchial hyperreactivity and an infiltration of lymphocytes and eosinophils into the airway submucosa. Animal models and clinical studies in humans have indicated an important role for T helper type 2 lymphocytes, producing IL-4, IL-5 and IL-13, in the pathogenesis of this disorder. However, although IL-4 and IL-13 have strong anti… CONTINUE READING

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