Characterization of Schistosome Tegumental Alkaline Phosphatase (SmAP)

@inproceedings{Bhardwaj2011CharacterizationOS,
  title={Characterization of Schistosome Tegumental Alkaline Phosphatase (SmAP)},
  author={Rita Bhardwaj and Patrick Skelly},
  booktitle={PLoS neglected tropical diseases},
  year={2011}
}
Schistosomes are parasitic platyhelminths that currently infect over 200 million people globally. The parasites can live for years in a putatively hostile environment - the blood of vertebrates. We have hypothesized that the unusual schistosome tegument (outer-covering) plays a role in protecting parasites in the blood; by impeding host immunological signaling pathways we suggest that tegumental molecules help create an immunologically privileged environment for schistosomes. In this work, we… CONTINUE READING
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