Characterization of Propylene Glycol-Mitigated Freeze/Thaw Agglomeration of a Frozen Liquid nOMV Vaccine Formulation by Static Light Scattering and Micro-Flow Imaging.

@article{Mensch2015CharacterizationOP,
  title={Characterization of Propylene Glycol-Mitigated Freeze/Thaw Agglomeration of a Frozen Liquid nOMV Vaccine Formulation by Static Light Scattering and Micro-Flow Imaging.},
  author={Christopher D Mensch and Harrison Davis and Jeffrey T. Blue},
  journal={PDA journal of pharmaceutical science and technology},
  year={2015},
  volume={69 4},
  pages={477-98}
}
UNLABELLED The purpose of this work was to investigate the susceptibility of an aluminum adjuvant and an aluminum-adjuvanted native outer membrane vesicle (nOMV) vaccine formulation to freeze/thaw-induced agglomeration using static light scattering and micro-flow Imaging analysis; and to evaluate the use of propylene glycol as a vaccine formulation… CONTINUE READING