Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice

@inproceedings{GualdrnLpez2018CharacterizationOP,
  title={Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice},
  author={Melisa Gualdr{\'o}n-L{\'o}pez and Erika L. Flannery and Niwat Kangwanrangsan and Vorada Chuenchob and Dietmar Fern{\'a}ndez-Orth and Joan Segu{\'i}-Barber and Felix Royo and Juan Manuel Falc{\'o}n-P{\'e}rez and Carmen Fern{\'a}ndez-Becerra and Marcus V G Lacerda and Stefan H Kappe and Jetsumon Sattabongkot and Juan Jos{\'e} Ramos Gonz{\'a}lez and Sebastian A Mikolajczak and Hernando A Del Portillo},
  booktitle={Front. Microbiol.},
  year={2018}
}
Exosomes are extracellular vesicles of endocytic origin containing molecular signatures implying the cell of origin; thus, they offer a unique opportunity to discover biomarkers of disease. Plasmodium vivax, responsible for more than half of all malaria cases outside Africa, is a major obstacle in the goal of malaria elimination due to the presence of dormant liver stages (hypnozoites), which after the initial infection may reactivate to cause disease. Hypnozoite infection is asymptomatic and… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 60 REFERENCES

World Malaria Report 2017

World Health Organization
  • Geneva: World Health Organization. Licence: CC BY-NC-SA 3.0 IGO.
  • 2017
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL