Characterization of Photofrin photobleaching for singlet oxygen dose estimation during photodynamic therapy of MLL cells in vitro.

Abstract

A singlet oxygen dose model is developed for PDT with Photofrin. The model is based on photosensitizer photobleaching kinetics, and incorporates both singlet oxygen and non-singlet oxygen mediated bleaching mechanisms. To test our model, in vitro experiments were performed in which MatLyLu (MLL) cells were incubated in Photofrin and then irradiated with 532… (More)

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Cite this paper

@article{Dysart2005CharacterizationOP, title={Characterization of Photofrin photobleaching for singlet oxygen dose estimation during photodynamic therapy of MLL cells in vitro.}, author={Jonathan S Dysart and Michael S. Patterson}, journal={Physics in medicine and biology}, year={2005}, volume={50 11}, pages={2597-616} }