Characterization of O-glycosylated precursors of insulin-like growth factor II by matrix-assisted laser desorption/ionization mass spectrometry.

Abstract

High molecular weight precursors of insulin-like growth factor II (IGF-II) were isolated from Cohn fraction IV of human plasma by ultrafiltration, affinity chromatography and reversed-phase high-performance liquid chromatography. Molecular weight determination by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) of two high molecular… (More)

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@article{Jespersen1996CharacterizationOO, title={Characterization of O-glycosylated precursors of insulin-like growth factor II by matrix-assisted laser desorption/ionization mass spectrometry.}, author={Sonja Jespersen and Joost A Koedam and Cok M Hoogerbrugge and Ubbo R. Tjaden and Jan van der Greef and J L van den Brande}, journal={Journal of mass spectrometry : JMS}, year={1996}, volume={31 8}, pages={893-900} }