Characterization of Nob3, a major quantitative trait locus for obesity and hyperglycemia on mouse chromosome 1.

Abstract

New Zealand obese (NZO) mice present a metabolic syndrome of obesity, insulin resistance, and diabetes. To identify chromosomal segments associated with these traits, we intercrossed NZO mice with the lean and diabetes-resistant C57BL/6J (B6) strain. Obesity and hyperglycemia in the (NZO x B6)F2 intercross population were predominantly due to a broad… (More)
DOI: 10.1152/physiolgenomics.00011.2009

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@article{Vogel2009CharacterizationON, title={Characterization of Nob3, a major quantitative trait locus for obesity and hyperglycemia on mouse chromosome 1.}, author={Heike Vogel and Matthias Nestler and Franz R{\"{u}schendorf and M Block and Sina Tischer and Reinhart Kluge and Annette Sch{\"{u}rmann and Hans-Georg Joost and Stephan Scherneck}, journal={Physiological genomics}, year={2009}, volume={38 2}, pages={226-32} }