Characterization of Neisseria gonorrhoeae protein II phase variation by use of monoclonal antibodies.

@article{Black1984CharacterizationON,
  title={Characterization of Neisseria gonorrhoeae protein II phase variation by use of monoclonal antibodies.},
  author={William J. Black and R. S. Schwalbe and Irving Nachamkin and Jonathan G. Cannon},
  journal={Infection and immunity},
  year={1984},
  volume={45 2},
  pages={453-7}
}
The protein II (P.II) outer membrane proteins of Neisseria gonorrhoeae, which have been implicated in gonococcal pathogenesis, have been previously shown to undergo a type of phase variation in which expression of any of several different forms of the proteins may be switched on or off. We identified six electrophoretically distinct forms of P.II proteins (designated P.IIa through P.IIf) within strain FA1090, and we isolated colonial variants of FA1090 that expressed only one of the six… CONTINUE READING