Characterization of Na(+)/H(+) antiporter activity in PC-Cl3 thyroid cells.


BACKGROUND/AIMS In thyroid cells, the intracellular pH plays a key role in the control of the iodide uptake, since iodide accumulation is associated with an intracellular acidification. In the present paper we studied the kinetic proprieties of the Na(+)/H(+) antiporter (NHE) and the molecular expression of different NHE isoforms in rat thyroid PC-Cl3 cells… (More)


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