Characterization of Mycobacterium avium clinical isolates in Japan using subspecies-specific insertion sequences, and identification of a new insertion sequence, ISMav6.

@article{Ichikawa2009CharacterizationOM,
  title={Characterization of Mycobacterium avium clinical isolates in Japan using subspecies-specific insertion sequences, and identification of a new insertion sequence, ISMav6.},
  author={Kazuya Ichikawa and Tetsuya Yagi and Makoto Moriyama and Takayuki Inagaki and Taku Nakagawa and Kei-ichi Uchiya and Toshiaki Nikai and Kenji Ogawa},
  journal={Journal of medical microbiology},
  year={2009},
  volume={58 Pt 7},
  pages={
          945-50
        }
}
Clinical isolates of Mycobacterium avium (n=81) from patients with pulmonary infections who were HIV-negative and isolates (n=33) from HIV-positive patients were subjected to genetic analysis by PCR detection of three M. avium-specific insertion sequences (IS901, IS1245 and IS1311), and nucleotide sequencing of the heat-shock protein 65 (hsp65) gene. All clinical isolates were identified as 'M. avium subspecies hominissuis' by sequence analysis of hsp65. Compared with clinical isolates of M… CONTINUE READING

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