Characterization of L-arginine transport by pulmonary artery endothelial cells.

@article{Greene1991CharacterizationOL,
  title={Characterization of L-arginine transport by pulmonary artery endothelial cells.},
  author={Barry Greene and Anthony J. Pacitti and Wiley W. Souba},
  journal={The American journal of physiology},
  year={1991},
  volume={264 4 Pt 1},
  pages={
          L351-6
        }
}
The transport of L-arginine by porcine pulmonary artery endothelial cells (PAECs) was characterized. Uptake of 50 microM L-arginine was time dependent and linear in the presence and absence of sodium, with approximately 70% of uptake occurring via a carrier-mediated Na(+)-independent process. Kinetic studies of saturable Na(+)-independent transport revealed two transport components: a high-affinity transporter [Michaelis constant (Km) = 304 +/- 23 microM, maximal transport velocity (Vmax) = 679… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

L-arginine-induced current in portal venous smooth muscle cells.

  • Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi
  • 2007
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Increased L-arginine uptake and inducible nitric oxide synthase activity in aortas of rats with heart failure.

  • American journal of physiology. Heart and circulatory physiology
  • 2001
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED