Characterization of Human Neural Progenitor Cells and Neurons Differentiated from Induced Pluripotent Stem Cells

@article{Apti2018CharacterizationOH,
  title={Characterization of Human Neural Progenitor Cells and Neurons Differentiated from Induced Pluripotent Stem Cells},
  author={{\'A}gota Ap{\'a}ti and T{\"u}nde Berecz and Eszter Szab{\'o} and Tam{\'a}s I. Orb{\'a}n and L{\'a}szl{\'o} Homolya and Bal{\'a}zs Sarkadi and J{\'a}nos M R{\'e}thelyi},
  journal={The FASEB Journal},
  year={2018},
  volume={32}
}
Most studies focusing on neural development and the mechanism of neurodevelopmental disorders are based on animal (rodent or avian) models or post mortem human samples. Thus, the observations derived from these studies cannot be directly translated into mechanistic insights of human neural development and regeneration. Human pluripotent stem cells, which can potentially be differentiated into any cell types of the body, offer a new perspective to overcome this limitation. In the present study…