Corpus ID: 89980456

Characterization of HIV-1 subtype B near full-length genome sequences identified at the start of HIV epidemic in South Africa

  title={Characterization of HIV-1 subtype B near full-length genome sequences identified at the start of HIV epidemic in South Africa},
  author={Adetayo Emmanuel Adegbenga Obasa},


Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes.
These methods allow the large-scale collection of HIV-1 NFLGs from populations infected primarily with subtype C, and provide materials for viral functional analyses and population-based molecular epidemiology studies that include analysis of viral genome chimerization. Expand
recombinant HIV-1 viruses from Cape Town, South Africa’, Infection
  • Genetics and Evolution,
  • 2015
HIV-1 Nomenclature Proposal
A clear and consistent genetic classification of human immunodeficiency virus-type 1 (HIV-1) strains continues to be of great utility in epidemiological tracking of the AIDS pandemic and in vaccineExpand
Identification of env subtypes in fourteen HIV type 1 isolates from south Africa.
The authors emphasize the need for ongoing molecular epidemiological analysis of HIV-1 subtypes to track the current epidemic in South Africa, and more rapid methods will facilitate subtyping to monitor the circulation and spread ofAIDS subpopulations in the country. Expand
The discovery of endogenous retroviruses
  • R. Weiss
  • Biology, Medicine
  • Retrovirology
  • 2006
Some of the key observations in birds and mammals that led to the discovery of ERV are recounted, and comment on their evolution, cross-species dispersion, and what remains to be elucidated. Expand
Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes
The genome of a new SIVcpz strain is sequenced and the subspecies identity of all known SIV cpz-infected chimpanzees is determined, by mitochondrial DNA analysis, and it is found that two chimpanzee subspecies in Africa harbour SIVCPz and that their respective viruses form two highly divergent (but subspecies-specific) phylogenetic lineages. Expand
Efficiencies of the NJp, Maximum Likelihood, and Bayesian Methods of Phylogenetic Construction for Compositional and Noncompositional Genes.
The computer simulations have shown that the NJp method generally gives a better performance than the other methods and therefore this method should be used in general whether the gene is compositional or it contains the mosaic DNA regions or not. Expand
HIV-1 subtype B: Traces of a pandemic.
This paper reviews the evolution of HIV-1B and its impact on the human population and suggests that several lineages have emerged from Haiti and reached other Caribbean and Latin American countries via short-distance dissemination. Expand
New insights into HIV epidemic in South Africa: key findings from the National HIV Prevalence, Incidence and Behaviour Survey, 2012
There is a need to scale up prevention methods that integrate biomedical, behavioural, social and structural prevention interventions to reverse the tide in the fight against HIV in South Africa. Expand
TEMPORARY REMOVAL: The global spread of HIV-1 subtype B epidemic.’, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
  • Elsevier B.V. doi: 10.1016/j.meegid.2016.05.041
  • 2016