Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK.

@article{Dimou2012CharacterizationOE,
  title={Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK.},
  author={Vassiliki Dimou and Hiran Dhanji and Rachel Pike and David Martin Livermore and Neil Woodford},
  journal={The Journal of antimicrobial chemotherapy},
  year={2012},
  volume={67 7},
  pages={1660-5}
}
OBJECTIVES To characterize UK clinical isolates of Enterobacteriaceae producing OXA-48-like carbapenemases and to compare their resistance plasmids. METHODS Twenty-six enterobacteria producing OXA-48-like enzymes were studied. These were from 22 diverse hospitals in the UK. Isolates of Escherichia coli and Klebsiella pneumoniae were assigned to clonal lineages by multilocus sequence typing. Carbapenemase genes and their genetic environments were characterized by PCR and sequencing. Resistance… CONTINUE READING
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