Characterization of Empathy Deficits following Prefrontal Brain Damage: The Role of the Right Ventromedial Prefrontal Cortex
@article{ShamayTsoory2003CharacterizationOE, title={Characterization of Empathy Deficits following Prefrontal Brain Damage: The Role of the Right Ventromedial Prefrontal Cortex}, author={Simone G. Shamay-Tsoory and Rachel Tomer and Barry Berger and Judith Aharon-Peretz}, journal={Journal of Cognitive Neuroscience}, year={2003}, volume={15}, pages={324-337} }
Impaired empathic response has been described in patients following brain injury, suggesting that empathy may be a fundamental aspect of the social behavior disturbed by brain damage. However, the neuroanatomical basis of impaired empathy has not been studied in detail. The empathic response of patients with localized lesions in the prefrontal cortex (n = 25) was compared to responses of patients with posterior (n = 17) and healthy control subjects (n = 19). To examine the cognitive processes…
465 Citations
Impairment in Cognitive and Affective Empathy in Patients with Brain Lesions: Anatomical and Cognitive Correlates
- Psychology, BiologyJournal of clinical and experimental neuropsychology
- 2004
Results indicate that patients with prefrontal lesions (especially those with lesions involving the orbitoprefrontal and medial regions) were significantly impaired in both cognitive and affective empathy as compared to parietal patients and healthy controls.
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- Psychology, BiologyCognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology
- 2005
It was indicated that patients with VM (but not dorsolateral) prefrontal lesions were significantly impaired in irony and faux pas but not in second-order false belief as compared with patients with posterior lesions and normal control subjects.
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- Psychology, BiologyNeuropsychologia
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Damage to the left ventromedial prefrontal cortex impacts affective theory of mind.
- Psychology, BiologySocial cognitive and affective neuroscience
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The results revealed that the left, and not the right vmPFC as indicated previously, is involved in affective ToM and that this deficit is associated with emotional intelligence.
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Three studies converge in support of the proposal that affective empathy--making inferences about how another person feels--engages at least the following areas: prefrontal cortex, orbitofrontal gyrus, anterior insula, anterior cingulate cortex, temporal pole, amygdala and temporoparietal junction.
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