Characterization of Edwardsiella tarda rpoN: roles in σ70 family regulation, growth, stress adaption and virulence toward fish

@article{Wang2011CharacterizationOE,
  title={Characterization of Edwardsiella tarda rpoN: roles in σ70 family regulation, growth, stress adaption and virulence toward fish},
  author={Keping Wang and Enfu Liu and Shanshan Song and Xiaobo Wang and Yunxia Zhu and Jiang Hai Ye and Huizhan Zhang},
  journal={Archives of Microbiology},
  year={2011},
  volume={194},
  pages={493-504}
}
Edwardsiella tarda EIB202, a Gram-negative pathogen with strong virulence, is an opportunistic pathogen capable of causing edwardsiellosis with high mortality to fish. Alternative sigma factor 54 (RpoN) is an important regulator of virulence and stress resistance genes in many bacterial species and mainly responsible for transcription of genes in nitrogen utilization. In this study, the in-frame rpoN deletion mutant was constructed to analyze the function of RpoN in Edwardsiella tarda firstly… CONTINUE READING