Characterization of Discrete Subpopulations of Progenitor Cells in Traumatic Human Extremity Wounds

@inproceedings{Woodard2014CharacterizationOD,
  title={Characterization of Discrete Subpopulations of Progenitor Cells in Traumatic Human Extremity Wounds},
  author={Geoffrey E. Woodard and Youngmi Ji and Gregory T. Christopherson and Karen Marie Wolcott and D J David J Hall and Wesley M Jackson and Leon J. Nesti},
  booktitle={PloS one},
  year={2014}
}
Here we show that distinct subpopulations of cells exist within traumatic human extremity wounds, each having the ability to differentiate into multiple cells types in vitro. A crude cell suspension derived from traumatized muscle was positively sorted for CD29, CD31, CD34, CD56 or CD91. The cell suspension was also simultaneously negatively sorted for either CD45 or CD117 to exclude hematopoietic stem cells. These subpopulations varied in terms their total numbers and their abilities to grow… CONTINUE READING