Characterization of Chemically Induced Liver Injuries Using Gene Co-Expression Modules

@inproceedings{Tawa2014CharacterizationOC,
  title={Characterization of Chemically Induced Liver Injuries Using Gene Co-Expression Modules},
  author={Gregory J. Tawa and Mohamed Diwan M. AbdulHameed and Xueping Yu and Kamal Kumar and Danielle L. Ippolito and John Arban Lewis and Jonathan D Stallings and Anders Wallqvist},
  booktitle={PloS one},
  year={2014}
}
Liver injuries due to ingestion or exposure to chemicals and industrial toxicants pose a serious health risk that may be hard to assess due to a lack of non-invasive diagnostic tests. Mapping chemical injuries to organ-specific damage and clinical outcomes via biomarkers or biomarker panels will provide the foundation for highly specific and robust diagnostic tests. Here, we have used DrugMatrix, a toxicogenomics database containing organ-specific gene expression data matched to dose-dependent… CONTINUE READING
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