Characterization of Ceramide Synthase 2

@article{Laviad2008CharacterizationOC,
  title={Characterization of Ceramide Synthase 2},
  author={Elad L. Laviad and L. Albee and I. Pankova-Kholmyansky and Sharon Epstein and Hyejung Park and A. Merrill and A. Futerman},
  journal={Journal of Biological Chemistry},
  year={2008},
  volume={283},
  pages={5677 - 5684}
}
Ceramide is an important lipid signaling molecule and a key intermediate in sphingolipid biosynthesis. Recent studies have implied a previously unappreciated role for the ceramide N-acyl chain length, inasmuch as ceramides containing specific fatty acids appear to play defined roles in cell physiology. The discovery of a family of mammalian ceramide synthases (CerS), each of which utilizes a restricted subset of acyl-CoAs for ceramide synthesis, strengthens this notion. We now report the… Expand
A Critical Role for Ceramide Synthase 2 in Liver Homeostasis
Ceramide metabolism in mouse tissue.
Ceramide synthases in biomedical research.
A fluorescent assay for ceramide synthase activity
Ceramide synthase 1 is regulated by proteasomal mediated turnover.
The Role of the Ceramide Acyl Chain Length in Neurodegeneration: Involvement of Ceramide Synthases
Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 36 REFERENCES
When Do Lasses (Longevity Assurance Genes) Become CerS (Ceramide Synthases)?
Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death.
Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P
  • R. Xu, Junfei Jin, +6 authors C. Mao
  • Biology, Medicine
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2006
...
1
2
3
4
...