Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis.

@article{Yi2014CharacterizationOC,
  title={Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis.},
  author={John S. Yi and A C Guidon and Susan Sparks and Robyn Osborne and Vern C. Juel and Janice M. Massey and Donald Sanders and Kent J. Weinhold and Jeffrey T. Guptill},
  journal={Journal of autoimmunity},
  year={2014},
  volume={52},
  pages={130-8}
}
Muscle specific tyrosine kinase myasthenia gravis (MuSK MG) is a form of autoimmune MG that predominantly affects women and has unique clinical features, including prominent bulbar weakness, muscle atrophy, and excellent response to therapeutic plasma exchange. Patients with MuSK MG have predominantly IgG4 autoantibodies directed against MuSK on the postsynaptic muscle membrane. Lymphocyte functionality has not been reported in this condition. The goal of this study was to characterize T cell… CONTINUE READING