Characterization of CD3+CD4-CD8- (double negative) T cells reconstitution in patients following hematopoietic stem-cell transplantation.

@article{Ye2011CharacterizationOC,
  title={Characterization of CD3+CD4-CD8- (double negative) T cells reconstitution in patients following hematopoietic stem-cell transplantation.},
  author={Haige Ye and Yingjun Chang and Xiangyu Zhao and Xiaojun Huang},
  journal={Transplant immunology},
  year={2011},
  volume={25 4},
  pages={180-6}
}
BACKGROUND CD3+CD4-CD8-double negative (DN) T cells, as a distinct subset of regulatory T cells (Tregs), played a pivotal role in patients following hematopoietic stem-cell transplantation. METHODS This study examines the behavior of CD3+CD4-CD8- double negative (DN) T cells in 73 patients at days 30, 60, 90 and 180 after allo-HSCT. RESULTS There was no significant difference in neutrophil and platelet engraftment between the higher and lower absolute counts of 30days DN Tregs (p=0.674, 0… CONTINUE READING