Characterization of CCL20 secretion by human epithelial vaginal cells: involvement in Langerhans cell precursor attraction.

@article{Cremel2005CharacterizationOC,
  title={Characterization of CCL20 secretion by human epithelial vaginal cells: involvement in Langerhans cell precursor attraction.},
  author={Magali Cremel and Willy Berlier and Hind Hamzeh and Fabrice Cognasse and Philip Lawrence and Christian Genin and Jean-Claude Bernengo and Cristen Lambert and Marie-Caroline Dieu-Nosjean and Olivier D{\'e}lezay},
  journal={Journal of leukocyte biology},
  year={2005},
  volume={78 1},
  pages={158-66}
}
Mucosa represents the main site of pathogen/cell interactions. The two main types of cells forming the epithelial structure [epithelial cells and Langerhans cells (LC)] coordinate the first defense responses to avoid infection. To evaluate the involvement of epithelial cells in the early steps leading to a specific adaptive immune response, we have studied the interactions between vaginal epithelial and LC through the establishment of a human vaginal epithelial mucosa. We demonstrate that… CONTINUE READING

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