Characterization of Bunyamwera virus defective interfering particles.

@article{Patel1992CharacterizationOB,
  title={Characterization of Bunyamwera virus defective interfering particles.},
  author={Arvind H Patel and Richard M. Elliott},
  journal={The Journal of general virology},
  year={1992},
  volume={73 ( Pt 2)},
  pages={389-96}
}
In an attempt to isolate conditional lethal amber nonsense mutants of Bunyamwera virus, five variants were found which produced small plaques on BHK and mouse L cells. Characterization of these variants by Northern blotting showed that they synthesized defective (subgenomic) RNAs derived from the L RNA segment. No subgenomic M or S segment RNAs were detected. The defective L RNAs were shown to be packaged into virus particles, and four of five preparations caused interference with the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…