Characterization of Bax and Bcl-2 in apoptosis after experimental traumatic brain injury in the rat

@article{Wennersten2002CharacterizationOB,
  title={Characterization of Bax and Bcl-2 in apoptosis after experimental traumatic brain injury in the rat},
  author={Andr{\'e} Wennersten and Staffan Holmin and T. G. Mathiesen},
  journal={Acta Neuropathologica},
  year={2002},
  volume={105},
  pages={281-288}
}
This study was undertaken to fulfill the need for additional data on the dynamics of Bax and Bcl-2 expression in conjunction to the cell death that ensues following experimental brain contusion. Adult Sprague-Dawley rats were subjected to a unilateral experimental controlled cortical contusion and killed at 1, 2, 4, 6 and 10 days post injury (dpi). Cell death was examined by the terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) method together with immunohistochemistry… CONTINUE READING
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