Characterization of 27-hydroxy-13-desmethyl spirolide C and 27-oxo-13,19-didesmethyl spirolide C. Further insights into the complex Adriatic Alexandrium ostenfeldii toxin profile.

@article{Ciminiello2010CharacterizationO2,
  title={Characterization of 27-hydroxy-13-desmethyl spirolide C and 27-oxo-13,19-didesmethyl spirolide C. Further insights into the complex Adriatic Alexandrium ostenfeldii toxin profile.},
  author={Patrizia Ciminiello and Carmela Dell'Aversano and Emma Dello Iacovo and Ernesto Fattorusso and Martino Forino and Laura Grauso and Luciana Tartaglione and Franca Guerrini and Laura Pezzolesi and Rossella Pistocchi},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2010},
  volume={56 8},
  pages={1327-33}
}
Alexandrium ostenfeldii is a widespread toxic dinoflagellate that has recently bloomed across the Adriatic Sea, seriously threatening both shellfish consumers and aquacultures. In 2007 we reported on preliminary studies carried out on field samples and cultures of A. ostenfeldii. At the time, along with three major spirolides - among which 27-hydroxy-13,19-didesmethyl spirolide C (3) proved to be a novel compound - a number of new minor spirolides were detected. Unfortunately, for all of them… CONTINUE READING

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