Characterization of 11p14-p12 deletion in WAGR syndrome by array CGH for identifying genes contributing to mental retardation and autism.

@article{Xu2008CharacterizationO1,
  title={Characterization of 11p14-p12 deletion in WAGR syndrome by array CGH for identifying genes contributing to mental retardation and autism.},
  author={Shunliang Xu and Joan C Han and Antonio Trejo Morales and Carolyn M Menzie and Keith M. Williams and Y-S Fan},
  journal={Cytogenetic and genome research},
  year={2008},
  volume={122 2},
  pages={
          181-7
        }
}
WAGR (Wilms tumor, Aniridia, Genitourinary malformations and mental Retardation) syndrome is a rare genomic disorder caused by deletion of the 11p14-p12 chromosome region. The majority of WAGR patients have mental retardation and behavioral problems, and more than 20% of the patients also have features of autism. While the Wilms tumor/genitourinary anomalies and aniridia are caused by deletion of WT1 and PAX6 respectively, the genomic cause of mental retardation and autism in WAGR syndrome… CONTINUE READING
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