Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells.

@article{Bunch1988CharacterizationAU,
  title={Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells.},
  author={Thomas A. Bunch and Yevgenya Grinblat and Lawrence S. B. Goldstein},
  journal={Nucleic acids research},
  year={1988},
  volume={16 3},
  pages={1043-61}
}
The promoter from the metallothionein gene may be a useful conditional promoter for the construction of chimeric genes to be expressed in Drosophila cells in culture. To explore this possibility the responses of the endogenous metallothionein gene and an in vitro constructed chimeric gene containing the metallothionein promoter were examined. Copper and cadmium, when added to the growth medium of Drosophila Schneider's line 2 cells, can produce a 30-100 fold induction of metallothionein mRNA… CONTINUE READING
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