Characterization and targeting of the murine alpha2-antiplasmin gene.


Alpha2-Antiplasmin (alpha2-AP) is the main physiological plasmin inhibitor in mammalian plasma. As a first step toward the generation of alpha2-AP deficient mice, the murine alpha2-AP gene was characterized and a targeting vector for homologous recombination in embryonic stem (ES) cells constructed. Alignment of nucleotide sequences obtained from genomic… (More)


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@article{Okada1997CharacterizationAT, title={Characterization and targeting of the murine alpha2-antiplasmin gene.}, author={K Okada and Henri Roger Lijnen and Mieke Dewerchin and Alexandra Belayew and Osamu Matsuo and D{\'e}sir{\'e} Collen and Ria Bernaerts}, journal={Thrombosis and haemostasis}, year={1997}, volume={78 3}, pages={1104-10} }