Characterization and species distribution of high affinity GTP-coupled receptors for human rantes and monocyte chemoattractant protein 1

  • G Van Riper, S Siciliano, +3 authors H Rosen
  • Published 1993 in The Journal of experimental medicine
Equilibrium binding studies with recombinant human chemoattractant cytokines Rantes and monocyte chemoattractant protein 1 (MCP-1) on monocytic THP-1 cells have allowed the functional identification of two distinct receptors for C-C chemokines. One is a novel oligospecific receptor with high affinity for Rantes (50% maximal inhibitory concentration [IC50… (More)