Characterization and osteogenic effects of mesenchymal stem cells on microbeads composed of hydroxyapatite nanoparticles/reconstituted collagen.

@article{Jeng2009CharacterizationAO,
  title={Characterization and osteogenic effects of mesenchymal stem cells on microbeads composed of hydroxyapatite nanoparticles/reconstituted collagen.},
  author={Long-Bin Jeng and Hui-Ying Chung and Tsung-Min Lin and Jyh-Ping Chen and Yi-Ling Chen and Yi-Lung Lu and Yng-Jiin Wang and Sophia Chia-Ning Chang},
  journal={Journal of biomedical materials research. Part A},
  year={2009},
  volume={91 3},
  pages={
          886-93
        }
}
Natural bone is comprised of nanosized blade-like crystals of hydroxyapatite grown in close contact with collagen (Col) fibers. Characteristics of artificial bone tissue differ considerably with those of natural ones, mainly from the unusual self-organizing interaction between the apatite crystals and the proteic components. Nanoparticle spheres of hydroxyapatite (n-HA), dispersed in reconstituted fibrous Col, were prepared in three weight ratios of 75:25, 65:35, and 50:50 (n-HA:Col). Bone… CONTINUE READING
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