Characterization and isolation of a C-reactive protein receptor from the human monocytic cell line U-937.

@article{Tebo1990CharacterizationAI,
  title={Characterization and isolation of a C-reactive protein receptor from the human monocytic cell line U-937.},
  author={Julie M. Tebo and Richard M. Mortensen},
  journal={Journal of immunology},
  year={1990},
  volume={144 1},
  pages={231-8}
}
Human C-reactive protein (CRP) is an acute phase reactant that is opsonic and an activator of macrophage tumoricidal function. CRP also activates the classical C cascade. These activities suggest that CRP might interact with monocytes/macrophages via specific receptors in a manner analogous to the interaction of IgG with FcR. With the use of radio-labeled human CRP, we have observed specific binding of CRP to human blood monocytes and the human monocytic cell line U-937. Binding was saturable… CONTINUE READING
26 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Similar Papers

Loading similar papers…