Characterization and improvement of RNA-Seq precision in quantitative transcript expression profiling

Abstract

MOTIVATION Measurement precision determines the power of any analysis to reliably identify significant signals, such as in screens for differential expression, independent of whether the experimental design incorporates replicates or not. With the compilation of large-scale RNA-Seq datasets with technical replicate samples, however, we can now, for the… (More)
DOI: 10.1093/bioinformatics/btr247

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