Characterization and identification of Sox2+ radial glia cells derived from rat embryonic cerebral cortex

@article{Li2011CharacterizationAI,
  title={Characterization and identification of Sox2+ radial glia cells derived from rat embryonic cerebral cortex},
  author={Haoming Li and Guohua Jin and Jianbing Qin and Meiling Tian and Jinhong Shi and Weiwei Yang and Xuefeng Tan and Xinhua Zhang and Linqing Zou},
  journal={Histochemistry and Cell Biology},
  year={2011},
  volume={136},
  pages={515-526}
}
During the central nervous system (CNS) development, radial glia cells (RGCs) play at least two essential roles, they contribute to neuronal production and the subsequent guidance of neuronal migration, whereas its precise distribution and contribution to cerebral cortex remains less understood. In this research, we used Vimentin as an astroglial marker and Sox2 as a neural progenitor marker to identify and investigate RGCs in rat cerebral cortex at embryonic day (E) 16.5. We found that the… CONTINUE READING
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