Characterization and genetic analysis of bovine alpha S1-casein I variant.

  title={Characterization and genetic analysis of bovine alpha S1-casein I variant.},
  author={Gesine L{\"u}hken and Anna Caroli and Eveline M Ibeagha-Awemu and Georg Erhardt},
  journal={Animal genetics},
  volume={40 4},
The aim of this study was to identify the molecular genetic origin underlying the I variant of alpha(s1)-casein and to develop a DNA-based test for this polymorphism as a tool for genetic analyses independent of milk sample testing. All coding exons and flanking regions of the alpha(s1)-casein gene were sequenced in DNA samples from cattle of known alpha(s1)-casein genotypes (BI, CI, II, CC), determined by isoelectric focusing of milk samples. A nucleotide substitution (A>T) in exon 11 (g… CONTINUE READING