Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease.

@article{Demeester2000CharacterizationAF,
  title={Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease.},
  author={N Demeester and Grace Castro and Catherine M Desrumaux and Catherine De Geitere and J. C. Fruchart and Patrick Santens and E Mulleners and Sebastiaan Engelborghs and Peter Paul De Deyn and Jo{\"e}l Vandekerckhove and Maryvonne Rosseneu and Christine Labeur},
  journal={Journal of lipid research},
  year={2000},
  volume={41 6},
  pages={963-74}
}
We investigated the lipoprotein distribution and composition in cerebrospinal fluid (CSF) in a group of patients with Alzheimer's disease (AD) or affected by other types of dementia in comparison to non-demented controls. We found slightly decreased apolipoprotein (apo)E and cholesterol concentrations in CSF of AD patients and moderately increased apoA-I concentrations, while in patients suffering from other types of dementia the apoA-I CSF concentration was increased. ApoA-IV concentrations… CONTINUE READING
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