Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma

@article{Dembinski2009CharacterizationAF,
  title={Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma},
  author={Jennifer L. Dembinski and Stefan Krauss},
  journal={Clinical & Experimental Metastasis},
  year={2009},
  volume={26},
  pages={611 - 623}
}
Evidence suggests that multiple tumors, including pancreatic adenocarcinoma, display heterogeneity in parameters that are critical for tumor formation, progression and metastasis. Understanding heterogeneity in solid tumors is increasingly providing a plethora of new diagnostic and therapeutic approaches. In this study, a particular focus was put on identifying a subpopulation of stem cell-like, slow cycling tumor cells in a pancreas adenocarcinoma cell lines. Using a label retention technique… CONTINUE READING
94 Citations
36 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 94 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Mesenchymal stem cell (MSC) edification; tumor microenvironment drives MSC differentation into tumor-associated fibroblasts that contribute to fibrovascular network expansion

  • J Dembinski, E Spaeth, K Sasser
  • PLoS ONE 4(4):e4992. doi: 10.1371/journal.pone…
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…