Characterization and expression of serotonin transporter genes in zebrafish.

  title={Characterization and expression of serotonin transporter genes in zebrafish.},
  author={Yuhong Wang and Rie Takai and Hidekatsu Yoshioka and Komei Shirabe},
  journal={The Tohoku journal of experimental medicine},
  volume={208 3},
To understand the development of serotonergic neurons in vertebrates, we used zebrafish as a model system. In this study we cloned two cDNAs (complementary DNAs) coding for serotonin transporter (SERT) from the zebrafish, named serta and sertb. The serta cDNA encodes a protein of 693 amino acids and showed high level of sequence identity with rat and human SERTs. In situ hybridization showed serta to be expressed in raphe nuclei, ventral posterior tuberculum and pineal organ. The expression of… CONTINUE READING


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Zebrafish, A Practical

  • C. Nüsslein-Volhard, R. Dahm
  • 2002
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