Characterization and correction of error in genome-wide IBD estimation for samples with population structure.

Abstract

The proportion of the genome that is shared identical by descent (IBD) between pairs of individuals is often estimated in studies involving genome-wide SNP data. These estimates can be used to check pedigrees, estimate heritability, and adjust association analyses. We focus on the method of moments technique as implemented in PLINK [Purcell et al., 2007… (More)
DOI: 10.1002/gepi.21737

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