Characterization and control of fungal morphology for improved production performance in biotechnology.

@article{Krull2013CharacterizationAC,
  title={Characterization and control of fungal morphology for improved production performance in biotechnology.},
  author={Rainer Krull and Thomas Wucherpfennig and Manely Eslahpazir Esfandabadi and Robert Walisko and Guido Melzer and Dietmar C. Hempel and Ingo Kampen and Arno Kwade and Christoph Wittmann},
  journal={Journal of biotechnology},
  year={2013},
  volume={163 2},
  pages={112-23}
}
Filamentous fungi have been widely applied in industrial biotechnology for many decades. In submerged culture processes, they typically exhibit a complex morphological life cycle that is related to production performance--a link that is of high interest for process optimization. The fungal forms can vary from dense spherical pellets to viscous mycelia. The resulting morphology has been shown to be influenced strongly by process parameters, including power input through stirring and aeration… CONTINUE READING
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