Characterization and cloning of the human splicing factor 9G8: a novel 35 kDa factor of the serine/arginine protein family.

@article{Cavaloc1994CharacterizationAC,
  title={Characterization and cloning of the human splicing factor 9G8: a novel 35 kDa factor of the serine/arginine protein family.},
  author={Yvon Cavaloc and Michel Popielarz and Jean-Paul Fuchs and Renata Gattoni and James St{\'e}venin},
  journal={The EMBO Journal},
  year={1994},
  volume={13}
}
By adopting a monoclonal antibody approach, we have identified a novel splicing factor of 35 kDa which we have termed 9G8. The isolation and characterization of cDNA clones indicate that 9G8 is a novel member of the serine/arginine (SR) splicing factor family because it includes an N‐terminal RNA binding domain (RBD) and a C‐terminal SR domain. The RNA binding domain of 9G8 is highly homologous to those of the SRp20 and RBP1 factors (79‐71% identity), but the homology is less pronounced in the… 
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