Characterization and N-terminal sequence of a heparan sulphate proteoglycan synthesized by endothelial cells in culture.

@article{Castillo1987CharacterizationAN,
  title={Characterization and N-terminal sequence of a heparan sulphate proteoglycan synthesized by endothelial cells in culture.},
  author={C J Castillo and P B Colburn and V. Buonassisi},
  journal={The Biochemical journal},
  year={1987},
  volume={247 3},
  pages={687-93}
}
We have isolated from the conditioned medium of an established endothelial cell line a heparan sulphate proteoglycan whose involvement in the inhibition of the extrinsic coagulation pathway was reported in previous studies [Colburn & Buonassisi (1982) Biochem. Biophys. Res. Commun. 104, 220-227]. The proteoglycan was purified by gel filtration and ion… CONTINUE READING