Characterization, expression, and mutation of the Lactococcus lactis galPMKTE genes, involved in galactose utilization via the Leloir pathway.

@article{Grossiord2003CharacterizationEA,
  title={Characterization, expression, and mutation of the Lactococcus lactis galPMKTE genes, involved in galactose utilization via the Leloir pathway.},
  author={Beno{\^i}t P Grossiord and Evert J Luesink and Elaine E. Vaughan and Alain Arnaud and Willem M de Vos},
  journal={Journal of bacteriology},
  year={2003},
  volume={185 3},
  pages={870-8}
}
A cluster containing five similarly oriented genes involved in the metabolism of galactose via the Leloir pathway in Lactococcus lactis subsp. cremoris MG1363 was cloned and characterized. The order of the genes is galPMKTE, and these genes encode a galactose permease (GalP), an aldose 1-epimerase (GalM), a galactokinase (GalK), a hexose-1-phosphate uridylyltransferase (GalT), and a UDP-glucose 4-epimerase (GalE), respectively. This genetic organization reflects the order of the metabolic… CONTINUE READING
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