Characterization, classification and alignment of protein-protein interfaces

  title={Characterization, classification and alignment of protein-protein interfaces},
  author={Hongbo Zhu},
Protein structural models provide essential information for the research on proteinprotein interactions. In this dissertation, we describe two projects on the analysis of protein interactions using structural information. The focus of the first is to characterize and classify different types of interactions. We discriminate between biological obligate and biological non-obligate interactions, and crystal packing contacts. To this end, we defined six interface properties and used them to compare… CONTINUE READING
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