Characteristics of vascular smooth muscle in the maternal resistance circulation during pregnancy in the rat.

@article{Meyer1993CharacteristicsOV,
  title={Characteristics of vascular smooth muscle in the maternal resistance circulation during pregnancy in the rat.},
  author={Markus Christian Meyer and Joseph E. Brayden and Margaret K McLaughlin},
  journal={American journal of obstetrics and gynecology},
  year={1993},
  volume={169 6},
  pages={1510-6}
}
OBJECTIVE Our purpose was to determine if pregnancy results in a decrease in arterial sensitivity to receptor-independent stimuli and a change in vascular smooth muscle membrane potential. STUDY DESIGN Mesenteric resistance arteries from late pregnant (n = 19) and age-matched virgin control (n = 20) Sprague-Dawley rats were studied in a pressurized arteriograph system or isometric myograph. RESULTS Arteries from pregnant rats were less sensitive to membrane depolarization by K+ than were… CONTINUE READING

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