Characteristics of the time-dependent slow inward current in adult human atrial single myocytes.

@article{Escande1986CharacteristicsOT,
  title={Characteristics of the time-dependent slow inward current in adult human atrial single myocytes.},
  author={Denis Escande and Alain Coulombe and Jean François Faivre and Edouard Coraboeuf},
  journal={Journal of molecular and cellular cardiology},
  year={1986},
  volume={18 5},
  pages={547-51}
}
The slow inward current isi plays a prominent role in impulse formation and slow conduction in the human heart. For this reason, it may be involved in a great variety of arrhythmias that occur clinically, particularly at the supraventricular level. isi also appears to be the major target of numerous cardioactive drugs daily administered to many patients. Difficulties encountered in voltage clamping human tissues, inevitably dissected from restricted zones of myocardium with inadequate geometry… CONTINUE READING

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