Characteristics of the prolactin stimulation of iodide uptake into mouse mammary gland explants.

@article{Rillema1997CharacteristicsOT,
  title={Characteristics of the prolactin stimulation of iodide uptake into mouse mammary gland explants.},
  author={James A. Rillema and D L Rowady},
  journal={Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine},
  year={1997},
  volume={215 4},
  pages={366-9}
}
We have recently reported that prolactin (PRL) stimulates iodide uptake into cultured mouse mammary tissues. This effect occurs in both TCA soluble and insoluble tissue fractions. The effect of PRL apparently involves an RNA-DNA-dependent mechanism, since actinomycin D and cyclohexamide abolish the PRL stimulation of iodide uptake and its incorporation into protein. Perchlorate and thiocyanate, inhibitors of the iodide transporter, also abolish the PRL effects on iodide uptake and incorporation… CONTINUE READING

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