• Corpus ID: 8844780

Characteristics of renal p-aminohippurate and urate excretion in rabbits.

  title={Characteristics of renal p-aminohippurate and urate excretion in rabbits.},
  author={V S Donoso and J. J. Grantham},
  journal={The Journal of laboratory and clinical medicine},
  volume={107 4},
  • V. Donoso, J. Grantham
  • Published 1986
  • Medicine, Biology
  • The Journal of laboratory and clinical medicine
Urate and p-aminohippurate (PAH) excretion was studied in New Zealand white rabbits to determine the extent to which the renal tubular handling of these organic anions by intact kidneys paralleled observations made in single isolated perfused tubules in vitro. At low plasma concentrations (less than 60 mumol/L) net reabsorption of urate was observed in the majority of animals; as plasma urate concentration was increased by infusing lithium urate, net urate secretion was demonstrated, the… 
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