Characteristics of rectal perception are altered in irritable bowel syndrome.

@article{Kwan2005CharacteristicsOR,
  title={Characteristics of rectal perception are altered in irritable bowel syndrome.},
  author={Chun L. Kwan and Nicholas E. Diamant and Kristi Mikula and Karen D. Davis},
  journal={Pain},
  year={2005},
  volume={113 1-2},
  pages={160-71}
}
A hallmark symptom of irritable bowel syndrome (IBS) is a lower pain threshold during rectal distension, but the mechanism underlying this disorder remains unclear. Examining the relationship between physiological and perceptual responses to rectal distension can provide insight into the underlying peripheral or central dysfunction in IBS. Therefore, we carried out a study of the rectal sensations of urge to defecate, pain and unpleasantness in relation to the varying states of the rectum. Ten… CONTINUE READING