Characteristics of prostate cancer in families potentially linked to the hereditary prostate cancer 1 (HPC1) locus.

@article{Grnberg1997CharacteristicsOP,
  title={Characteristics of prostate cancer in families potentially linked to the hereditary prostate cancer 1 (HPC1) locus.},
  author={Henrik Gr{\"o}nberg and Sarah D. Isaacs and Jeffrey R. Smith and John D. Carpten and G. Steven Bova and Diha Freije and Jianfeng Xu and Deborah A. Meyers and Francis S. Collins and Jeffrey M. Trent and Patrick Walsh and William B Isaacs},
  journal={JAMA},
  year={1997},
  volume={278 15},
  pages={1251-5}
}
CONTEXT Approximately 9% of prostate cancer cases have been estimated to result from inheritance of mutated prostate cancer susceptibility genes. Few data exist as to whether there are clinical differences between prostate cancers that are inherited and those that occur in the general population. OBJECTIVE To investigate phenotypic characteristics of families potentially linked to the hereditary prostate cancer 1 (HPC1) locus on chromosome 1q24-25. DESIGN Retrospective case study in which… CONTINUE READING

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