Characteristics of hydatidiform moles: analysis of a prospective series with p57 immunohistochemistry and molecular genotyping

@article{Banet2014CharacteristicsOH,
  title={Characteristics of hydatidiform moles: analysis of a prospective series with p57 immunohistochemistry and molecular genotyping},
  author={Natalie Banet and Cheryl Descipio and Kathleen M Murphy and Katie F Beierl and Emily J. Adams and Russell Vang and Brigitte M. Ronnett},
  journal={Modern Pathology},
  year={2014},
  volume={27},
  pages={238-254}
}
Immunohistochemical analysis of cyclin-dependent kinase inhibitor 1C (CDKN1C, p57, Kip2) expression and molecular genotyping accurately classify hydatidiform moles into complete and partial types and distinguish these from non-molar specimens. Characteristics of a prospective series of all potentially molar specimens encountered in a large gynecologic pathology practice are summarized. Initially, all specimens were subjected to both analyses; this was later modified to triage cases for… CONTINUE READING

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